Toxic shock syndrome toxin 1(TSST-1) and endotoxin levels in patients with severe sepsis.
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چکیده
منابع مشابه
Identification of Toxic Shock Syndrome Toxin-1 (TSST-1) gene in Staphylococcus aureus isolated from bovine mastitis milk
Staphylococcus aureus is a major causative pathogen of clinical and subclinical mastitis of dairy domestic ruminants. This agent produces a variety of extracellular toxins and virulence factors including Toxic Shock Syndrome Toxin-1 (TSST-1) which is the major cause of Toxic Shock Syndrome (TSS). In this study 58 S. aureus isolates obtained from 9 dairy herds in East and West Azerbaijan provinc...
متن کامل[Evaluation of anti-toxic shock syndrome toxin-1 (TSST-1) antibody in severely burned patients].
序 文 広範囲熱傷患者は,皮 膚常在菌である黄色ブ ド ウ球菌が繁殖 しやす く,近 年のメチシ リン耐性株 の流行に伴い,創 感染ひいては敗血症に陥 り治療 に難渋する.特 に当施設においては,黄 色ブ ドウ 球菌の94%が メチシ リン耐性で さらにその うち 96%がTSST-1産 生株であ り1),それが感染症の重 篤化になんらかの影響を及ぼしていることが想定 される.そ こで研究の第一段階として,広 範囲熱 傷患者血清中のTSST-1に 対す る抗体 である抗 TSST-1抗 体価を測定 し,臨 床的意義について検 討した. 材料 と方法 対象は気道内,創 部等よりマンニット分解,食 塩耐性,コ アグラーゼ陽性の基準にて同定 した Staphylococcusaureusが 分離検出 された広範囲 熱傷患者16例 である(平 均年齢44.8±17.4歳,平 均熱傷面積48....
متن کاملThe effect of endotoxin adsorber hemoperfusion on microcirculation in patients with severe sepsis and septic shock
Introduction Microcirculatory dysfunction may result in multiple organ dysfunction during severe sepsis and septic shock. (1) A meta-analysis of randomized trials showed that polymyxin B hemoperfusion (PMX-HP), plasma exchange, and hemofiltration were associated with lower mortality. (2) Mesenteric microcirculation was better maintained with polymyxin B hemoperfusion in one rat sepsis study. (3...
متن کاملPrevalence of Antibody to Toxic Shock Syndrome Toxin-1 in Burn Patients
BACKGROUND Burn wounds lack normal barriers that protect against pathogenic bacteria, and burn patients are easily colonized and infected by Staphylococcus aureus. Toxic shock syndrome (TSS) is a rare but fatal disease caused by S. aureus. A lack of detectable antibodies to TSS toxin-1 (TSST-1) in serum indicates susceptibility to TSS. METHODS A total of 207 patients (169 men and 38 women; me...
متن کاملVaccination with plasmid DNA encoding a mutant toxic shock syndrome toxin-1 ameliorates toxin-induced lethal shock in mice.
Staphylococcal toxic shock syndrome toxin-1 (TSST-1), a superantigenic toxin produced by Staphylococcus (S.) aureus, is a major cause of septic shock and toxic shock syndrome. To investigate whether vaccination with a plasmid DNA encoding a non-toxic mutant TSST-1 (mTSST-1) can protect mice against wild-type TSST-1-induced lethal shock, the mice were intranasally immunized with the plasmid DNA ...
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ژورنال
عنوان ژورنال: Nihon Kyukyu Igakukai Zasshi
سال: 1998
ISSN: 1883-3772,0915-924X
DOI: 10.3893/jjaam.9.53